In this report, we assess the predictive capacity of an environmental risk score (E-score) used to predict colorectal cancer (CRC) in caucasian men and women between 48 and 78 years old. We use the PLCO screening trial to assess the calibration and validation of this previously developed E-score.

The report is organized as follows. The PLCO tab above reports the distribution of key variables in the PLCO data set used in the formulation of the E-score (demographics), and information about the outcome of interest (CRC outcome).

Under the E-score tab drop-down menu, we show:

In the future, we will assess the calibration/validation of a risk score that incorporates genetic information as well (G-score).